Nerve Regeneration by Wild Mushroom Hericium erinaceus

By Dr. Markho Rafael


Out of the kitchen, into the pharmacy, the gourmet mushroom Lion's Mane (Hericium erinaceus) with its unique flavor resembling lobster or shrimp appears to also possess likewise unique medicinal properties. It has been found to stimulate nerve and myelin regeneration, which may be beneficial in many neurological conditions. World renowned medicinal mushroom expert Paul Stamets suggests its potential application in conditions such as Alzheimer's, dementia, multiple sclerosis and muscular dystrophy. (134)

Lion's Mane Mushroom (Hericium erinaceus) is known in the wild from North America, Europe, China and Japan. It grows on many species of deciduous trees, in particular oak, walnut, beech, maple and sycamore.

The active compounds that have received the most attention for their nerve regenerating properties are named erinacines, a series of low molecular weight molecules that are able to pass through the blood brain barrier - an essential attribute for any medicinal compound expected to be able to effect healing on myelin or nerve tissue. (152, 153, 154)

In Japan, there are two patents on extracts of Hericium erinaceus. The first was filed in the 1990's for a process of extraction that yields what has been named "Nerve Growth Stimulant Factor." (150, 151) The second from 2004 is for a water extract of Hericium erinaceus. It is likewise used to stimulate nerve regeneration. (155)

Although recent research on Hericium erinaceus extract has focused on its powerful effect on healing nerve tissue, in Traditional Chinese Medicine Lion's Mane Mushroom was used primarily for stomach conditions and cancers of the digestive organs.

Two modern studies have confirmed this ancient wisdom. One done in 1985 showed positive results for treating atrophic gastritis. Another conducted a decade later, in 1995, showed some ameliorating effect on hepatoma, with a marked life extension of treated patients. (156)

Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any herb (or mushroom) except as advised by a licensed medical practitioner.

Credit: Thank you to Paul Stamets for source material.




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